A 70 kg male patient performs spirometry before and after receiving 2.5 mg albuterol delivered via metered dose inhaler. Which of the following FEV1 results would indicate a significant response to the bronchodilator?

  1. 5% increase in FEV1​
  2. ​8% increase in FEV1
  3. 10% increase in FEV1
  4. 12% increase in FEV1


A 12% increase post bronchodilator of the FEV1 is the minimum increase necessary to be considered a significant response.